Innate and adaptive immunity in atherosclerosis
نویسندگان
چکیده
منابع مشابه
Innate and adaptive immunity in the pathogenesis of atherosclerosis.
This review considers critically the evidence for the involvement of mediators of innate and acquired immunity in various stages of atherosclerosis. Rapidly mobilized arms of innate immunity, including phagocytic leukocytes, complement, and proinflammatory cytokines, contribute to atherogenesis. In addition, adaptive immunity, with its T cells, antibodies, and immunoregulatory cytokines, powerf...
متن کاملInnate immunity in atherosclerosis.
recognition of lipid and glycolipid antigens by CD1d. The finding that CD1d-activating lipids may accumulate in hyperlipidemic subjects supports a role for NK T cells in bridging hyperlipidemia and inflammation [10] . Another immune cell, the Th17 cell producing IL-17, and its role in atherosclerosis has been much debated due to recent apparently conflicting data [11–13] . In the third article,...
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ژورنال
عنوان ژورنال: Seminars in Immunopathology
سال: 2009
ISSN: 1863-2297,1863-2300
DOI: 10.1007/s00281-009-0153-8